We ARE hiring at all levels

please contact Alex directly for more information!

The Holehouse Lab will open in January 2020. However, Alex is physically at Washington University now and is available to meet with prospective students/postdocs/research scientists at any point. Lab members can expect to work in a highly interdisciplinary environment with active collaboration both within the lab and with colleagues around the world. There will also be cookies.


(Starting January 2020)
Assistant Professor
Washington University School of Medicine, Department of Biochemistry & Molecular Biophysics

Alex S. Holehouse

Contact: alex.holehouse{at]

Postdoc Washington University in St. Louis (Biomedical Engineering)
Washington University in St. Louis (Computational Biophysics)
Bioinformatician Icahn School of Medicine at Mount Sinai
M.Sc. Imperial College London (Computer Science )
M.Bioch. University of Oxford (Molecular & Cellular Biochemistry)

Hometown: “Northern Europe”

Favorite activity outside of lab: Playing ultimate frisbee and cooking for my hungry, hungry wife.

Favorite food: Ramen? Chicken Madras? Prosciutto? Too many options…

Graduate Students


"JJ" - Jhullian Jamille Alston

Joint with the Soranno lab

Graduate student in the Biophysics, Biochemistry, and Structural Biology graduate program

Contact: alstonj{at]

Research Interests: Combining experimental and computational methods to understand the role of intrinsically disordered regions in telomere assembly and dysregulation.

Education: University of Maryland Baltimore County, BA (Biology)

Hometown: Tempe, Arizona

Favorite Activity Outside of Lab: Weight lifting and cooking new dishes

Favorite Food: Lasagna or anything with cheese (except broccoli)



We are hiring at all levels!

For undergraduate students: We are looking for undergraduates with strong programming skills who want to apply their abilities to real world biological questions. A range of projects (from software engineering to machine learning) are available, and we can tailor projects to your interests, goals, and long-term career objectives.

For graduate students: A background in computational biology/biophysics is helpful but definitely not essential. More important is a track record of inquiry, good quantitative skills, self-motivation, and strong communication skills. Current graduate students in any graduate program at WashU (DBBS/BME/Physics/CS etc.) should contact Alex to set up a time to meet. Prospective graduate students should probably apply to one of the DBBS programs. Feel free to contact Alex directly for more information on the graduate programs at Wash U.

For postdocs/research scientists: We are actively looking for a wet-lab postdoc or research scientist to spearhead the experimental side of the lab. Specifically, we are interested in a candidate with experience in yeast cell biology, a strong sense of independence and initiative, and a desire to fundamentally shape the lab’s work. If you’re interested in the opportunity to drive an experimental portion of the lab (with extensive resources at your disposal) while learning a wide range of computational skills please reach out.

We are also looking for postdocs with experience in one or more of computational biology, biophysics, bioinformatics, systems biology, or machine learning. Strong programming and quantitative skills required.